FLCN antibody (N-Term)

Catalog No. ABIN2788829

The Rabbit Polyclonal anti-FLCN antibody has been validated for WB. It is suitable to detect FLCN in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig and Horse.

Quick Overview for FLCN antibody (N-Term) (ABIN2788829)

Target: FLCN (Folliculin (FLCN))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FLCN Antibody

Binding Specificity: N-Term

Sequence: EEGGIQMNSR MRAHSPAEGA SVESSSPGPK KSDMCEGCRS LAAGHPGYIS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FLCN. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 579 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: FLCN

Target Type: Amino Acid

Background: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax.
Alias Symbols: BHD, DKFZp547A118, FLCL, FLJ45004, FLJ99377, MGC17998, MGC23445
Protein Interaction Partner: FBXW11, BAG3, gag-pol, TP53BP1, APP, UBC, PRKAA2, FNIP1,
Protein Size: 579

Molecular Weight: 64 kDa

Gene ID: 201163

NCBI Accession: NM_144997, NP_659434

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization