VNN2 antibody (C-Term)

Catalog No. ABIN2788913

Product Details anti-VNN2 Antibody

Target: VNN2 (Vanin 2 (VNN2))

Binding Specificity: C-Term

Reactivity: Human, Cow, Horse, Dog, Pig, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VNN2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FRGFISRDGF NFTELFENAG NLTVCQKELC CHLSYRMLQK EENEVYVLGA

Predicted Reactivity: Cow: 79%, Dog: 89%, Horse: 86%, Human: 100%, Pig: 93%, Sheep: 86%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against VNN2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VNN2

Target: VNN2 (Vanin 2 (VNN2))

Alternative Name: VNN2 (VNN2 Products)

Background: This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FOAP-4, GPI-80
Protein Interaction Partner: ITGB2,
Protein Size: 520

Molecular Weight: 57 kDa

Gene ID: 8875

NCBI Accession: NM_004665, NP_004656

UniProt: O95498