CCT3 antibody (C-Term)

Catalog No. ABIN2788916

The Rabbit Polyclonal anti-CCT3 antibody has been validated for WB. It is suitable to detect CCT3 in samples from Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse and Rabbit.

Quick Overview for CCT3 antibody (C-Term) (ABIN2788916)

Target: CCT3 (Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCT3 Antibody

Binding Specificity: C-Term

Sequence: KELGIWEPLA VKLQTYKTAV ETAVLLLRID DIVSGHKKKG DDQSRQGGAP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CCT3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 545 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCT3

Target: CCT3 (Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3))

Alternative Name: CCT3

Background: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.
Alias Symbols: CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5
Protein Interaction Partner: FUS, HUWE1, UBC, TP53, MIPOL1, CDC20, NEDD1, LGALS3BP, SUMO3, TUBG1, SUMO2, MDM2, RNF2, BMI1, SUZ12, PPP4R2, LRRC47, CCT2, CCT4, CCT7, TRIM28, VARS, EEF1G, COPA, CCT6A, ACACA, PARK2, FBXW4, IGSF8, HDAC11, HDAC6, HDAC3, ILK, ICAM1, CDK9, CDK5, CDK2, CD81,
Protein Size: 545

Molecular Weight: 60 kDa

Gene ID: 7203

NCBI Accession: NM_005998, NP_005989

UniProt: P49368