NDUFS8 antibody (C-Term)

Catalog No. ABIN2788917

The Rabbit Polyclonal anti-NDUFS8 antibody (ABIN2788917) specifically detects NDUFS8 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for NDUFS8 antibody (C-Term) (ABIN2788917)

Target: NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFS8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDUFS8 Antibody

Binding Specificity: C-Term

Sequence: CKLCEAICPA QAITIEAEPR ADGSRRTTRY DIDMTKCIYC GFCQEACPVD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NDUFS8. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 210 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFS8

Target: NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))

Alternative Name: NDUFS8

Background: This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
Alias Symbols: CI23KD, TYKY, CI-23k
Protein Interaction Partner: MDM2, vpr, SURF1, SDHA, RPLP0, RAB5B, PSEN1, OPA1, NDUFV2, NDUFS6, NDUFV1, NDUFS3, NDUFS2, NDUFS1, MPV17, HSPA9, DHODH, CYC1, COX15, ABCC2, NDUFS7, RHOT2, NDUFAF3, SAMM50, UBC, GEM, ICT1,
Protein Size: 210

Molecular Weight: 23 kDa

Gene ID: 4728

NCBI Accession: NM_002496, NP_002487

UniProt: O00217