TBCD antibody (N-Term)

Catalog No. ABIN2788948

The Rabbit Polyclonal anti-TBCD antibody has been validated for WB. It is suitable to detect TBCD in samples from Human.

Quick Overview for TBCD antibody (N-Term) (ABIN2788948)

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBCD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBCD Antibody

Binding Specificity: N-Term

Sequence: KLVQRLGLTF LKPKVAAWRY QRGCRSLAAN LQLLTQGQSE QKPLILTEDD

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TBCD. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1192 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBCD

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Alternative Name: TBCD

Background: Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex, interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Alias Symbols: KIAA0988
Protein Interaction Partner: UBC, SUMO1, NEDD8, VPS25, APEH, ACBD3, SH3GLB2, WDR12, VPS29, RPUSD2, GORASP2, ATG7, TOM1, NMI, CUL3, TSN, STAT3, STAT1, SNX2, SARS, NASP, ME1, HIST1H1C, GTF2A1, POLR2I, SMAD9, APP, ACD, POT1, TERF1, Tubb4b, Tubb5, DEXI, ARL2, TBCE, TUBB, XRCC6, PPP2CA,
Protein Size: 1192

Molecular Weight: 131 kDa

Gene ID: 6904

NCBI Accession: NM_005993, NP_005984

UniProt: Q9BTW9

Pathways: Cell-Cell Junction Organization