DUSP9 antibody (Middle Region)

Catalog No. ABIN2788979

The Rabbit Polyclonal anti-DUSP9 antibody has been validated for WB. It is suitable to detect DUSP9 in samples from Human, Mouse, Rat, Horse, Cow, Guinea Pig, Dog, Rabbit and Saccharomyces cerevisiae.

Quick Overview for DUSP9 antibody (Middle Region) (ABIN2788979)

Target: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Reactivity: Human, Mouse, Rat, Horse, Cow, Guinea Pig, Dog, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUSP9 Antibody

Binding Specificity: Middle Region

Sequence: SSMAPVPGPV PVVGLGSLCL GSDCSDAESE ADRDSMSCGL DSEGATPPPV

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Yeast: 85%

Characteristics: This is a rabbit polyclonal antibody against DUSP9. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DUSP9

Target: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Alternative Name: DUSP9

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.
Alias Symbols: MKP-4, MKP4
Protein Interaction Partner: FAM96B, MAPK11, MAPK14, MMS19, UBC, GSK3B, CDK4, VCP, MAPK3, MAPK1,
Protein Size: 384

Molecular Weight: 42 kDa

Gene ID: 1852

NCBI Accession: NM_001395, NP_001386

UniProt: Q99956