Cyclin K antibody (Middle Region)

Catalog No. ABIN2788983

This Rabbit Polyclonal antibody specifically detects Cyclin K in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Cyclin K antibody (Middle Region) (ABIN2788983)

Target: Cyclin K (CCNK)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin K antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin K Antibody

Binding Specificity: Middle Region

Sequence: GDDPKEEVMV LERILLQTIK FDLQVEHPYQ FLLKYAKQLK GDKNKIQKLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CCNK. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 354 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin K

Target: Cyclin K (CCNK)

Alternative Name: CCNK

Background: The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.
Alias Symbols: CPR4, MGC9113
Protein Interaction Partner: LZTS2, RBPMS, NDC80, BHLHE40, AES, PIN1, HECW2, MMS19, UBC, PAXIP1, BARD1, CDK12, ATXN1, MYC, ELAVL1, USHBP1, TSC22D4, HMG20A, CCDC85B, CDK9, KRTAP4-12, NECAB2, CEP76, RFX6, STX11, POLR2A, KCNRG, FKBP6, EFEMP2, DVL3, RHOXF2, CDK18, CDK2,
Protein Size: 354

Molecular Weight: 39 kDa

Gene ID: 8812

NCBI Accession: NM_003858, NP_003849

UniProt: C9J9Q3