Cyclin K antibody (AA 80-160)

Catalog No. ABIN7227662

The Rabbit Polyclonal anti-Cyclin K antibody (ABIN7227662) specifically detects Cyclin K in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Cyclin K antibody (AA 80-160) (ABIN7227662)

Target: Cyclin K (CCNK)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin K antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cyclin K Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-CCNK Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCNK protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCNK protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cyclin K

Target: Cyclin K (CCNK)

Alternative Name: CCNK

Background: Cyclin-KThe protein encoded by CCNK (Cyclin K) is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. CCNK product may play a dual role in regulating CDK and RNA polymerase II activities. CCNK is a Protein Coding gene. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and HIV Life Cycle.

Molecular Weight: 63kD

Gene ID: 8812

UniProt: O75909