P4HA1 antibody (Middle Region)

Catalog No. ABIN2788989

The Rabbit Polyclonal anti-P4HA1 antibody has been validated for WB. It is suitable to detect P4HA1 in samples from Human, Rat, Mouse, Dog, Pig, Cow and Horse.

Quick Overview for P4HA1 antibody (Middle Region) (ABIN2788989)

Target: P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P4HA1 Antibody

Binding Specificity: Middle Region

Sequence: TKKLLELDPE HQRANGNLKY FEYIMAKEKD VNKSASDDQS DQKTTPKKKG

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against P4HA1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 534 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for P4HA1

Target: P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))

Alternative Name: P4HA1

Background: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: P4HA
Protein Interaction Partner: IRS4, UBC, WWOX, HDAC10, UBL4A, CFTR, CUL3, ELAVL1, CDK9, IRF7, EBNA-LP, SMN1, MYC,
Protein Size: 534

Molecular Weight: 59 kDa

Gene ID: 5033

NCBI Accession: NM_000917, NP_000908

UniProt: P13674