MED18 antibody (Middle Region)

Catalog No. ABIN2789031

Product Details anti-MED18 Antibody

Target: MED18 (Mediator Complex Subunit 18 (MED18))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED18 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PWHLRYLGQP EMGDKNRHAL VRNCVDIATS ENLTDFLMEM GFRMDHEFVA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MED18. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 208 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MED18

Target: MED18 (Mediator Complex Subunit 18 (MED18))

Alternative Name: MED18 (MED18 Products)

Background: MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II.
Alias Symbols: FLJ20045, p28b
Protein Interaction Partner: HOMEZ, TRIM39, MED20, CAMK2B, UBC, CDK19, CDK8, MED19, MED26, EPAS1, MED11, MED8, MED4, MED16, MED24, MED21, MED14, PIP4K2B, MED1, MED30, MED10, MED28, MED29, MED18, MED15, MED31, MED6, MED13, MED12, MED27, MED17, MED23, TADA2A, MED22, CCNC, MED9, USP49,
Protein Size: 208

Molecular Weight: 23 kDa

Gene ID: 54797

NCBI Accession: NM_017638, NP_060108

UniProt: Q9BUE0

Pathways: Regulation of Lipid Metabolism by PPARalpha