NSP5 antibody (N-Term)

Catalog No. ABIN2789055

This Rabbit Polyclonal antibody specifically detects NSP5 in WB. It exhibits reactivity toward Human, Rat, Dog, Horse and Rabbit.

Quick Overview for NSP5 antibody (N-Term) (ABIN2789055)

Target: NSP5 (SPECC1) (Sperm Antigen with Calponin Homology and Coiled-Coil Domains 1 (SPECC1))

Reactivity: Human, Rat, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NSP5 Antibody

Binding Specificity: N-Term

Sequence: RTPSTKPKQE NEGGEKAALE SQVRELLAEA KAKDSEINRL RSELKKYKEK

Predicted Reactivity: Dog: 79%, Horse: 79%, Human: 100%, Rabbit: 87%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SPECC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPECC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 790 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NSP5

Target: NSP5 (SPECC1) (Sperm Antigen with Calponin Homology and Coiled-Coil Domains 1 (SPECC1))

Alternative Name: SPECC1

Background: The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FLJ36955, HCMOGT-1, NSP, SPECC1
Protein Interaction Partner: RNF2, HECW2, PAN2, UBC, TRAF2, DAXX, Poc1b, Mau2, Trim69, Stag2, Erh, Cdk1,
Protein Size: 790

Molecular Weight: 87 kDa

Gene ID: 92521

NCBI Accession: NM_152904, NP_690868

UniProt: Q5M775