RASAL1 antibody (C-Term)

Catalog No. ABIN2789073

The Rabbit Polyclonal anti-RASAL1 antibody has been validated for WB. It is suitable to detect RASAL1 in samples from Human and Pig.

Quick Overview for RASAL1 antibody (C-Term) (ABIN2789073)

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASAL1 Antibody

Binding Specificity: C-Term

Sequence: DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG

Predicted Reactivity: Human: 100%, Pig: 83%

Characteristics: This is a rabbit polyclonal antibody against RASAL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 804 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RASAL1

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Alternative Name: RASAL1

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Alias Symbols: RASAL
Protein Interaction Partner: RPS6KA3, NAPRT, RRAGB, UBC, PITX1,
Protein Size: 804

Molecular Weight: 88 kDa

Gene ID: 8437

NCBI Accession: NM_004658, NP_004649

UniProt: O95294