MRPS11 antibody (Middle Region)

Catalog No. ABIN2789181

Product Details anti-MRPS11 Antibody

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GTEGFRNAKK GTGIAAQTAG IAAAARAKQK GVIHIRVVVK GLGPGRLSAM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MRPS11. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 161 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS11

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Alternative Name: MRPS11 (MRPS11 Products)

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.
Alias Symbols: FLJ22512, FLJ23406, HCC-2
Protein Interaction Partner: CEP57, CEP76, SRPK1, MRPS14, SAMM50, RPL23, RPS26, RPS23, RPL9, CUL3, COPS5, UBC, ICT1,
Protein Size: 161

Molecular Weight: 17 kDa

Gene ID: 64963

NCBI Accession: NM_001145838, NP_001139310

UniProt: E7EP84