MRPL3 antibody (N-Term)

Catalog No. ABIN2789211

The Rabbit Polyclonal anti-MRPL3 antibody has been validated for WB. It is suitable to detect MRPL3 in samples from Human, Mouse, Rat, Cow, Rabbit, Dog and Guinea Pig.

Quick Overview for MRPL3 antibody (N-Term) (ABIN2789211)

Target: MRPL3 (Mitochondrial Ribosomal Protein L3 (MRPL3))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL3 Antibody

Binding Specificity: N-Term

Sequence: THIWLFVRGL HGKSGTWWDE HLSEENVPFI KQLVSDEDKA QLASKLCPLK

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MRPL3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 348 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL3

Target: MRPL3 (Mitochondrial Ribosomal Protein L3 (MRPL3))

Alternative Name: MRPL3

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.
Alias Symbols: MRL3, RPML3
Protein Interaction Partner: UBC, MRPS27, mug82, ICT1, C1QBP, MRPL55, MRPL10, MRPL52, MRPL9, MRPL41, MRPS9, MRPL17, MRPL39, MRPL4, MRPL13, MRPL42, MRPL46, MRPL19, RPS18, RPS15, MRPL12, MRPL23, NDUFS3, APP, CAND1,
Protein Size: 348

Molecular Weight: 38 kDa

Gene ID: 11222

NCBI Accession: NM_007208, NP_009139

UniProt: P09001