MRPS31 antibody (N-Term)

Catalog No. ABIN2789214

Product Details anti-MRPS31 Antibody

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS31 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LTVRHGTVRY RSSALLARTK NNIQRYFGTN SVICSKKDKQ SVRTEETSKE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MRPS31. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS31

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Alternative Name: MRPS31 (MRPS31 Products)

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes, however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
Alias Symbols: IMOGN38, MRP-S31, S31mt
Protein Interaction Partner: GRSF1, UBC, SMURF2, PARK2, STAT3, ESR2, SARNP, CPSF7, SRPRB, FLOT1, CUL3, ICT1, USP42, EIF6, LYST,
Protein Size: 395

Molecular Weight: 43 kDa

Gene ID: 10240

NCBI Accession: NM_005830, NP_005821

UniProt: Q92665