FBXL8 antibody (N-Term)

Catalog No. ABIN2789253

This anti-FBXL8 antibody is a Rabbit Polyclonal antibody detecting FBXL8 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Pig and Rabbit.

Quick Overview for FBXL8 antibody (N-Term) (ABIN2789253)

Target: FBXL8 (F-Box and Leucine-Rich Repeat Protein 8 (FBXL8))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXL8 Antibody

Binding Specificity: N-Term

Sequence: ECELEGMLPP YLSACLDHIH NLRLEFEPSR KPSRRAAIEL LMVLAGRAPG

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 92%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against FBXL8. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 374 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXL8

Target: FBXL8 (F-Box and Leucine-Rich Repeat Protein 8 (FBXL8))

Alternative Name: FBXL8

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78 % sequence identity with the mouse protein.
Alias Symbols: FBL8, FLJ11278, MGC19959
Protein Interaction Partner: SKP1, ORC4, HSP90AA1, CUL1,
Protein Size: 374

Molecular Weight: 40 kDa

Gene ID: 55336

NCBI Accession: NM_018378, NP_060848

UniProt: Q96CD0