FBXL8 antibody (N-Term)

Catalog No. ABIN2789254

This Rabbit Polyclonal antibody specifically detects FBXL8 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Pig and Guinea Pig.

Quick Overview for FBXL8 antibody (N-Term) (ABIN2789254)

Target: FBXL8 (F-Box and Leucine-Rich Repeat Protein 8 (FBXL8))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXL8 Antibody

Binding Specificity: N-Term

Sequence: KPSRRAAIEL LMVLAGRAPG LRGLRLECRG EKPLFDAGRD VLEAVHAVCG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXL8. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 374 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXL8

Target: FBXL8 (F-Box and Leucine-Rich Repeat Protein 8 (FBXL8))

Alternative Name: FBXL8

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78 % sequence identity with the mouse protein.
Alias Symbols: FBL8, FLJ11278, MGC19959
Protein Interaction Partner: SKP1, ORC4, HSP90AA1, CUL1,
Protein Size: 374

Molecular Weight: 40 kDa

Gene ID: 55336

NCBI Accession: NM_018378, NP_060848

UniProt: Q96CD0