CD68 antibody (N-Term)

Catalog No. ABIN2789336

This Rabbit Polyclonal antibody specifically detects CD68 in WB. It exhibits reactivity toward Human, Cow and Horse.

Quick Overview for CD68 antibody (N-Term) (ABIN2789336)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD68 Antibody

Binding Specificity: N-Term

Sequence: LLAAQGTGND CPHKKSATLL PSFTVTPTVT ESTGTTSHRT TKSHKTTTHR

Predicted Reactivity: Cow: 93%, Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CD68. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 354 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages.
Alias Symbols: DKFZp686M18236, GP110, SCARD1, LAMP4
Protein Interaction Partner: ADRB2, RALGDS,
Protein Size: 354

Molecular Weight: 37 kDa

Gene ID: 968

NCBI Accession: NM_001251, NP_001242

UniProt: P34810