CD1a antibody (C-Term)

Catalog No. ABIN2789348

This Rabbit Polyclonal antibody specifically detects CD1a in WB. It exhibits reactivity toward Human, Mouse, Dog, Rat, Pig, Cow, Guinea Pig, Horse and Sheep.

Quick Overview for CD1a antibody (C-Term) (ABIN2789348)

Target: CD1a

Reactivity: Human, Mouse, Dog, Rat, Pig, Cow, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1a antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1a Antibody

Binding Specificity: C-Term

Sequence: KPEAWLSHGP SPGPGHLQLV CHVSGFYPKP VWVMWMRGEQ EQQGTQRGDI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 79%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against CD1A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD1a

Target: CD1a

Alternative Name: CD1A

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Alias Symbols: CD1, FCB6, HTA1, R4, T6
Protein Interaction Partner: UBTD1, KCTD5, DGAT1, VWA5A, B2M,
Protein Size: 327

Molecular Weight: 37 kDa

Gene ID: 909

NCBI Accession: NM_001763, NP_001754

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process