PGD antibody (N-Term)

Catalog No. ABIN2789349

Product Details anti-PGD Antibody

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Saccharomyces cerevisiae, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DFIEKLVPLL DTGDIIIDGG NSEYRDTTRR CRDLKAKGIL FVGSGVSGGE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 85%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PGD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of PGD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PGD

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: PGD (PGD Products)

Background: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
Alias Symbols: 6PGD
Protein Interaction Partner: SUMO2, UBC, NEDD8, SUMO1, WWOX, EIF4H, THOP1, TGM2, TCEA1, SORD, RPS6KA1, LDHB, LDHA, HMGB2, PDIA3, GNAI3, GLA, G6PD, EEF2, ALDH7A1, ALDH9A1, TXNDC5, C12orf10, CHORDC1, YWHAQ, AHSA1, NDRG1, YWHAG, YWHAB, IQCB1, CDK4, CDK2, ISG15, TERF1, USPL1, LSM8, GBE1,
Protein Size: 483

Molecular Weight: 53 kDa

Gene ID: 5226

NCBI Accession: NM_002631, NP_002622

UniProt: P52209