OSCAR antibody (C-Term)

Catalog No. ABIN2789362

This anti-OSCAR antibody is a Rabbit Polyclonal antibody detecting OSCAR in WB. Suitable for Human.

Quick Overview for OSCAR antibody (C-Term) (ABIN2789362)

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSCAR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OSCAR Antibody

Binding Specificity: C-Term

Sequence: LSQRSEVLVI SWEDSGSSDY TRGNLVRLGL AGLVLISLGA LVTFDWRSQN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against OSCAR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 252 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OSCAR

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Alternative Name: OSCAR

Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC33613, PIGR3
Protein Interaction Partner: FCAR,
Protein Size: 252

Molecular Weight: 27 kDa

Gene ID: 126014

NCBI Accession: NM_133168, NP_573398