OSCAR antibody (AA 205-231)

Catalog No. ABIN3032104

Product Details anti-OSCAR Antibody

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Binding Specificity: AA 205-231

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSCAR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 205-231 from the human protein was used as the immunogen for this OSCAR antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the OSCAR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the OSCAR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for OSCAR

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Alternative Name: OSCAR (OSCAR Products)

Synonyms: OSCAR antibody, mOSCAR-M3 antibody, mOSCAR antibody, mOSCAR-M1 antibody, mOSCAR-M2 antibody, PIGR3 antibody, PIgR-3 antibody, RGD1559897 antibody, osteoclast associated, immunoglobulin-like receptor antibody, osteoclast-associated immunoglobulin-like receptor antibody, osteoclast associated receptor antibody, OSCAR antibody, LOC748876 antibody, Oscar antibody

Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q8IYS5