NPL antibody (N-Term)

Catalog No. ABIN2789414

This Rabbit Polyclonal antibody specifically detects NPL in WB. It exhibits reactivity toward Human, Rat, Dog, Horse, Pig, Cow and Guinea Pig.

Quick Overview for NPL antibody (N-Term) (ABIN2789414)

Target: NPL (N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) (NPL))

Reactivity: Human, Rat, Dog, Horse, Pig, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPL Antibody

Binding Specificity: N-Term

Sequence: SERRQVAEEW VTKGKDKLDQ VIIHVGALSL KESQELAQHA AEIGADGIAV

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NPL. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPL

Target: NPL (N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) (NPL))

Alternative Name: NPL

Background: This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: C1orf13, DHDPS1, MGC149582, MGC61869, NPL1, c112, NAL, C112
Protein Interaction Partner: NPL, WDYHV1, APP,
Protein Size: 230

Molecular Weight: 25 kDa

Gene ID: 80896

NCBI Accession: NM_001200052, NP_001186981

UniProt: Q9BXD5