CD81 antibody (C-Term)

Catalog No. ABIN2789419

Product Details anti-CD81 Antibody

Target: CD81

Binding Specificity: C-Term

Reactivity: Human, Goat, Sheep, Dog, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LKNNLCPSGS NIISNLFKED CHQKIDDLFS GKLYLIGIAA IVVAVIMIFE

Predicted Reactivity: Cow: 83%, Dog: 93%, Goat: 83%, Horse: 75%, Human: 100%, Pig: 86%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against CD81. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human CD81

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CD81 antibody (ABIN2789419)

Sukreet, Pereira Braga, An, Adamec, Cui, Zempleni: "Ultrasonication of Milk Decreases the Content of Exosomes and MicroRNAs in an Exosome-Defined Rodent Diet." in: The Journal of nutrition, Vol. 152, Issue 4, pp. 961-970, (2022) (PubMed).

Piao, Na, Seo, Hong, Sohn, Kwon, Lee, Kim: "Effects of general anaesthesia with an inhalational anaesthetic agent on the expression of exosomes in rats." in: International journal of medical sciences, Vol. 19, Issue 9, pp. 1399-1407, (2022) (PubMed).

Target Details for CD81

Target: CD81

Alternative Name: CD81 (CD81 Products)

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: S5.7, CVID6, TAPA1, TSPAN28
Protein Size: 274

Molecular Weight: 30 kDa

Gene ID: 975

NCBI Accession: NM_001297649, NP_001284578

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C