MC4R antibody (N-Term)

Catalog No. ABIN2789422

This anti-MC4R antibody is a Rabbit Polyclonal antibody detecting MC4R in WB. Suitable for Human, Rat, Mouse, Sheep, Rabbit, Cow, Dog, Horse, Guinea Pig and Goat.

Quick Overview for MC4R antibody (N-Term) (ABIN2789422)

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivity: Human, Rat, Mouse, Sheep, Rabbit, Cow, Dog, Horse, Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC4R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MC4R Antibody

Binding Specificity: N-Term

Sequence: VNSTHRGMHT SLHLWNRSSY RLHSNASESL GKGYSDGGCY EQLFVSPEVF

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against MC4R. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 332 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Alternative Name: MC4R

Background: The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
Alias Symbols: MGC126851, MGC138197
Protein Interaction Partner: NPM1, IL1RAP, MGRN1, ATRNL1, AGRP, PRKACA, ASIP, POMC, NPY, MC1R, ADRBK1,
Protein Size: 332

Molecular Weight: 37 kDa

Gene ID: 4160

NCBI Accession: NM_005912, NP_005903

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour