NAGA antibody (Middle Region)

Catalog No. ABIN2789447

The Rabbit Polyclonal anti-NAGA antibody is suitable to detect NAGA in samples from Human, Rat, Dog, Horse, Pig, Rabbit and Cow. It has been validated for WB.

Quick Overview for NAGA antibody (Middle Region) (ABIN2789447)

Target: NAGA (N-Acetylgalactosaminidase, alpha (NAGA))

Reactivity: Human, Rat, Dog, Horse, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAGA Antibody

Binding Specificity: Middle Region

Sequence: CFSTPEERAQ GYPKMAAALN ATGRPIAFSC SWPAYEGGLP PRVNYSLLAD

Predicted Reactivity: Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NAGA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human NAGA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 411 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NAGA

Target: NAGA (N-Acetylgalactosaminidase, alpha (NAGA))

Alternative Name: NAGA

Background: NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).
Alias Symbols: D22S674, GALB
Protein Interaction Partner: APP, FBXO6, UBC, GNGT1,
Protein Size: 411

Molecular Weight: 45 kDa

Gene ID: 4668

NCBI Accession: NM_000262, NP_000253

UniProt: P17050