NAGA antibody (Middle Region)
Quick Overview for NAGA antibody (Middle Region) (ABIN2789447)
Target
See all NAGA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- CFSTPEERAQ GYPKMAAALN ATGRPIAFSC SWPAYEGGLP PRVNYSLLAD
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Predicted Reactivity
- Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 79%
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Characteristics
- This is a rabbit polyclonal antibody against NAGA. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human NAGA
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 411 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NAGA (N-Acetylgalactosaminidase, alpha (NAGA))
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Alternative Name
- NAGA
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Background
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NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).
Alias Symbols: D22S674, GALB
Protein Interaction Partner: APP, FBXO6, UBC, GNGT1,
Protein Size: 411 -
Molecular Weight
- 45 kDa
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Gene ID
- 4668
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NCBI Accession
- NM_000262, NP_000253
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UniProt
- P17050
Target
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