Midkine antibody (C-Term)

Catalog No. ABIN2789494

This Rabbit Polyclonal antibody specifically detects Midkine in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow and Rabbit.

Quick Overview for Midkine antibody (C-Term) (ABIN2789494)

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Midkine antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Midkine Antibody

Binding Specificity: C-Term

Sequence: CDGGTGTKVR QGTLKKARYN AQCQETIRVT KPCTPKTKAK AKAKKGKGKD

Predicted Reactivity: Cow: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MDK. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 143 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Midkine

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Alternative Name: MDK

Background: Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis.
Alias Symbols: FLJ27379, MK, NEGF2
Protein Interaction Partner: SRPK2, UBQLN4, MAPK6, TSPAN1, RPL18A, SDC4, STAT1, LRP2, TGM1, SDC3, SDC1, PTPRZ1, NCL, MDK, JAK2, JAK1, LRP1, ALK, TUBB2B, NID2, TUBA1A, NID1, NCAM1, ACTG1,
Protein Size: 143

Molecular Weight: 16 kDa

Gene ID: 4192

NCBI Accession: NM_002391, NP_002382

UniProt: P21741

Pathways: RTK Signaling, M Phase, Skeletal Muscle Fiber Development