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KIR2DL1 antibody (C-Term)

KIR2DL1 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789507
  • Target See all KIR2DL1 Antibodies
    KIR2DL1 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
    Binding Specificity
    • 15
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 47
    • 2
    • 1
    • 1
    Human
    Host
    • 39
    • 9
    Rabbit
    Clonality
    • 40
    • 8
    Polyclonal
    Conjugate
    • 16
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIR2DL1 antibody is un-conjugated
    Application
    • 37
    • 13
    • 13
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Sequence
    DEQDPQEVTY TQLNHCVFTQ RKITRPSQRP KTPPTDIIVY TELPNAESRS
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against KIR2DL1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product KIR2DL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 348 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KIR2DL1 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
    Alternative Name
    KIR2DL1 (KIR2DL1 Products)
    Synonyms
    NKAT antibody, NKAT1 antibody, p58.1 antibody, CD158A antibody, KIR221 antibody, KIR-K64 antibody, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 antibody, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 antibody, KIR2DL1 antibody
    Background
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
    Alias Symbols: CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1
    Protein Interaction Partner: HLA-C,
    Protein Size: 348
    Molecular Weight
    38 kDa
    Gene ID
    3802
    NCBI Accession
    NM_014218, NP_055033
    UniProt
    P43626
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