CCR10 antibody (Middle Region)

Catalog No. ABIN2789531

Product Details anti-CCR10 Antibody

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARALPAGPRP STPGRAHLVS VIVWLLSLLL ALPALLFSQD GQREGQRRCR

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CCR10. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 362 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCR10

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Alternative Name: CCR10 (CCR10 Products)

Background: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27, CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.
Alias Symbols: GPR2
Protein Interaction Partner: CCL28, CXCL13, CCL27, CCL25, CCL19, CCR7, CCL7, CCL2, PRRC2A, CCL21,
Protein Size: 362

Molecular Weight: 40 kDa

Gene ID: 2826

NCBI Accession: NM_016602, NP_057686

UniProt: P46092