IL3RA antibody (Middle Region)

Catalog No. ABIN2789610

This anti-IL3RA antibody is a Rabbit Polyclonal antibody detecting IL3RA in WB. Suitable for Human.

Quick Overview for IL3RA antibody (Middle Region) (ABIN2789610)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL3RA Antibody

Binding Specificity: Middle Region

Sequence: APADVQYDLY LNVANRRQQY ECLHYKTDAQ GTRIGCRFDD ISRLSSGSQS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IL3RA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human IL3RA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: IL3RA

Background: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
Protein Interaction Partner: LNX1, FOXP1, SGK2, SAE1, NR0B2, GNA12, CDC25A, CDK1, PPP1CC, JAK1, IL3, CSF2RB, CSF2, CISH, JAK2,
Protein Size: 299

Molecular Weight: 32 kDa

Gene ID: 3563

Pathways: JAK-STAT Signaling