PEX14 antibody (C-Term)

Catalog No. ABIN2789633

The Rabbit Polyclonal anti-PEX14 antibody has been validated for WB. It is suitable to detect PEX14 in samples from Human, Mouse, Rat, Horse, Guinea Pig, Zebrafish (Danio rerio) and Dog.

Quick Overview for PEX14 antibody (C-Term) (ABIN2789633)

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Reactivity: Human, Mouse, Rat, Horse, Guinea Pig, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEX14 Antibody

Binding Specificity: C-Term

Sequence: EKREDKEDEE DEEDDDVSHV DEEDCLGVQR EDRRGGDGQI NEQVEKLRRP

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PEX14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PEX14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: PEX14

Background: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
Protein Interaction Partner: UBC, SLC27A2, TUBA4A, TTC1, TUBB2B, TUBB8, TUBB, ATAD1, TUBB6, FAR1, DYNC2H1, TUBG2, CNOT1, CCT5, DHRS4, IQGAP2, CCT8, CCT2, CCT4, CCT7, TUBB4B, TUBB4A, TUBB3, LRPPRC, DNM1L, PEX16, ARHGEF2, IQGAP1, AGPS, PEX3, GNPAT, TUBA1A, TUBB2A, CCT3, TCP1, PEX5, PEX
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 5195

Pathways: Maintenance of Protein Location