FGF18 antibody (C-Term)

Catalog No. ABIN2789639

The Rabbit Polyclonal anti-FGF18 antibody has been validated for WB. It is suitable to detect FGF18 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep and Horse.

Quick Overview for FGF18 antibody (C-Term) (ABIN2789639)

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGF18 Antibody

Binding Specificity: C-Term

Sequence: GKPDGTSKEC VFIEKVLENN YTALMSAKYS GWYVGFTKKG RPRKGPKTRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against FGF18. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FGF18

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 207 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FGF18

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Alternative Name: FGF18

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
Alias Symbols: FGF-18, ZFGF5
Protein Interaction Partner: LYAR, FGFR2, FGFR1, FGFR4, FGFR3,
Protein Size: 207

Molecular Weight: 21 kDa

Gene ID: 8817

NCBI Accession: NM_003862, NP_003853

UniProt: O76093

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway