ICOSLG antibody (C-Term)

Catalog No. ABIN2789695

The Rabbit Polyclonal anti-ICOSLG antibody has been validated for WB. It is suitable to detect ICOSLG in samples from Human.

Quick Overview for ICOSLG antibody (C-Term) (ABIN2789695)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ICOSLG Antibody

Binding Specificity: C-Term

Sequence: YDVVSVLRIA RTPSVNIGCC IENVLLQQNL TVGSQTGNDI GERDKITENP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ICOSLG. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 302 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: ICOSLG

Background: ICOSLG is a ligand for the T-cell-specific cell surface receptor ICOS. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. ICOSLG could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Alias Symbols: B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS
Protein Interaction Partner: ICOS,
Protein Size: 302

Molecular Weight: 33 kDa

Gene ID: 23308

NCBI Accession: NM_015259, NP_056074

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation