Sorting Nexin 1 antibody (N-Term)

Catalog No. ABIN2789705

The Rabbit Polyclonal anti-Sorting Nexin 1 antibody has been validated for WB and IHC. It is suitable to detect Sorting Nexin 1 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit and Horse.

Quick Overview for Sorting Nexin 1 antibody (N-Term) (ABIN2789705)

Target: Sorting Nexin 1 (SNX1)

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Sorting Nexin 1 Antibody

Binding Specificity: N-Term

Sequence: EDIFTGAAVV SKHQSPKITT SLLPINNGSK ENGIHEEQDQ EPQDLFADAT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SNX1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 557 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sorting Nexin 1

Target: Sorting Nexin 1 (SNX1)

Alternative Name: SNX1

Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: HsT17379, MGC8664, SNX1A, Vps5, VPS5
Protein Interaction Partner: SNX32, FUNDC1, CMTM5, REEP6, RTN4, AGTRAP, ARL6IP1, RABAC1, RTN3, UBC, MAT2B, GSPT2, ATG7, UGDH, STAT1, SHMT2, NASP, GARS, CTTN, ATP6V1C1, SNX6, ARFIP2, APP, DNAJC13, HGS, UFD1L, TK1, ATXN7, SNX2, VPS35, ACVR2B, ACVR1B, SNX1, LEPR, F2R, PDGFRB, INSR, EGFR
Protein Size: 557

Molecular Weight: 63 kDa

Gene ID: 6642

NCBI Accession: NM_001242933, NP_001229862

UniProt: Q13596