ARL1 antibody (C-Term)

Catalog No. ABIN2789707

Product Details anti-ARL1 Antibody

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKSELVAMLE EEELRKAILV VFANKQDMEQ AMTSSEMANS LGLPALKDRK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against ARL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 181 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARL1

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Alternative Name: ARL1 (ARL1 Products)

Background: The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.
Alias Symbols: ARFL1
Protein Interaction Partner: STAU1, ASB10, ASB1, RNF2, EGFR, MMS19, CUL3, ARFIP2, UBC, MYC, MME, SCOC, COPG2, GOLGA4, GOLGA1, GCC1, GCC2, CDK5RAP3,
Protein Size: 181

Molecular Weight: 20 kDa

Gene ID: 400

NCBI Accession: NM_001177, NP_001168

UniProt: P40616