SMC6 antibody (C-Term)

Catalog No. ABIN2789722

The Rabbit Polyclonal anti-SMC6 antibody (ABIN2789722) specifically detects SMC6 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse and Saccharomyces cerevisiae samples.

Quick Overview for SMC6 antibody (C-Term) (ABIN2789722)

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMC6 Antibody

Binding Specificity: C-Term

Sequence: MADSQRFRQF ILLTPQSMSS LPSSKLIRIL RMSDPERGQT TLPFRPVTQE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against SMC6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SMC6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1091 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMC6

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Alternative Name: SMC6

Background: SMC6 is a core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Alias Symbols: FLJ22116, FLJ35534, SMC6L1
Protein Interaction Partner: UBC, NSMCE1, NSMCE2, SMC6, NDNL2, NSMCE4A, SMC5, SUMO1, EID3, ALK,
Protein Size: 1091

Molecular Weight: 126 kDa

Gene ID: 79677

NCBI Accession: NM_024624, NP_078900

UniProt: Q96SB8