SMC6 antibody (C-Term)

Catalog No. ABIN2789722

This anti-SMC6 antibody is a Rabbit Polyclonal antibody detecting SMC6 in WB. Suitable for Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse and Saccharomyces cerevisiae.

Quick Overview for SMC6 antibody (C-Term) (ABIN2789722)

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMC6 Antibody

Binding Specificity: C-Term

Sequence: MADSQRFRQF ILLTPQSMSS LPSSKLIRIL RMSDPERGQT TLPFRPVTQE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against SMC6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SMC6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1091 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMC6

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Alternative Name: SMC6

Background: SMC6 is a core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Alias Symbols: FLJ22116, FLJ35534, SMC6L1
Protein Interaction Partner: UBC, NSMCE1, NSMCE2, SMC6, NDNL2, NSMCE4A, SMC5, SUMO1, EID3, ALK,
Protein Size: 1091

Molecular Weight: 126 kDa

Gene ID: 79677

NCBI Accession: NM_024624, NP_078900

UniProt: Q96SB8