CCKAR antibody (N-Term)

Catalog No. ABIN2789734

The Rabbit Polyclonal anti-CCKAR antibody has been validated for WB. It is suitable to detect CCKAR in samples from Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for CCKAR antibody (N-Term) (ABIN2789734)

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKAR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCKAR Antibody

Binding Specificity: N-Term

Sequence: GLENETLFCL DQPRPSKEWQ PAVQILLYSL IFLLSVLGNT LVITVLIRNK

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CCKAR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 428 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: CCKAR

Background: This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
Alias Symbols: CCK-A, CCK1-R, CCKRA
Protein Interaction Partner: CCKBR, CCKAR, CCK,
Protein Size: 428

Molecular Weight: 48 kDa

Gene ID: 886

NCBI Accession: NM_000730, NP_000721

UniProt: P32238

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour