GMDS antibody (C-Term)

Catalog No. ABIN2789736

This anti-GMDS antibody is a Rabbit Polyclonal antibody detecting GMDS in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for GMDS antibody (C-Term) (ABIN2789736)

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMDS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GMDS Antibody

Binding Specificity: C-Term

Sequence: WEGKNENEVG RCKETGKVHV TVDLKYYRPT EVDFLQGDCT KAKQKLNWKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against GMDS. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 342 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GMDS

Target: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Alternative Name: GMDS

Background: GDP-mannose 4,6-dehydratase catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans.
Alias Symbols: GMD, SDR3E1
Protein Interaction Partner: WDYHV1, GMDS, SUMO2, TATDN1, NSFL1C, RAP1GDS1, PTMA, CTH, CAPN2, ATIC, BAG3, UBC, BLVRB, TNKS,
Protein Size: 342

Molecular Weight: 39 kDa

Gene ID: 2762

NCBI Accession: NM_001253846, NP_001240775

UniProt: E9PI88