BANF1 antibody (Middle Region)

Catalog No. ABIN2789779

This Rabbit Polyclonal antibody specifically detects BANF1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for BANF1 antibody (Middle Region) (ABIN2789779)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BANF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BANF1 Antibody

Binding Specificity: Middle Region

Sequence: FDKAYVVLGQ FLVLKKDEDL FREWLKDTCG ANAKQSRDCF GCLREWCDAF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against BANF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human BANF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 89 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Alternative Name: BANF1

Background: The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Alias Symbols: BAF, BCRP1, D14S1460, MGC111161
Protein Interaction Partner: UBC, ERBB2IP, HIST1H3B, EMD, FBL, CRX, ATP6V1B1, LUC7L3, TMPO, EHMT2, SET, EVC2, ZNF428, LMNB2, DPY30, SMOC2, APTX, ACIN1, CBX3, PSIP1, CBX1, SUB1, CD2BP2, MDC1, BCL7C, MTA2, BANF1, CUL4A, CHAF1B, XPC, TUFM, SNRPD3, SMARCE1, SMARCC2, SMARCA2, TRA2B, DPF2,
Protein Size: 89

Molecular Weight: 10 kDa

Gene ID: 8815

NCBI Accession: NM_003860, NP_003851

UniProt: O75531