PSTPIP1 antibody (N-Term)

Catalog No. ABIN2789789

This anti-PSTPIP1 antibody is a Rabbit Polyclonal antibody detecting PSTPIP1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Pig and Rabbit.

Quick Overview for PSTPIP1 antibody (N-Term) (ABIN2789789)

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSTPIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSTPIP1 Antibody

Binding Specificity: N-Term

Sequence: HIQLALTLRE ELRSLEEFRE RQKEQRKKYE AVMDRVQKSK LSLYKKAMES

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 79%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PSTPIP1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 416 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSTPIP1

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Alternative Name: PSTPIP1

Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alias Symbols: CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Protein Interaction Partner: RTP5, TRAF3IP3, FBXL18, SH2D4A, PCDHB14, UBE2W, FAM90A1, PRPF31, LSM4, BUB3, ZNF175, TULP3, SPG7, SDCBP, MVP, WASL, DNM2, MED28, SHBG, KHDRBS1, WAS, TUBB, WIPF1, HSPA1A, CARS, ACTB, PTPN18, WASF2, WASF1, CD2AP, PTPN12, MEFV, ABL1, CD2, FASLG, BZW2, RPL36,
Protein Size: 416

Molecular Weight: 47 kDa

Gene ID: 9051

NCBI Accession: NM_003978, NP_003969

UniProt: O43586