PSTPIP1 antibody (N-Term)

Catalog No. ABIN2789789

The Rabbit Polyclonal anti-PSTPIP1 antibody (ABIN2789789) specifically detects PSTPIP1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Pig and Rabbit samples.

Quick Overview for PSTPIP1 antibody (N-Term) (ABIN2789789)

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSTPIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSTPIP1 Antibody

Binding Specificity: N-Term

Sequence: HIQLALTLRE ELRSLEEFRE RQKEQRKKYE AVMDRVQKSK LSLYKKAMES

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 79%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PSTPIP1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 416 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSTPIP1

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Alternative Name: PSTPIP1

Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alias Symbols: CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Protein Interaction Partner: RTP5, TRAF3IP3, FBXL18, SH2D4A, PCDHB14, UBE2W, FAM90A1, PRPF31, LSM4, BUB3, ZNF175, TULP3, SPG7, SDCBP, MVP, WASL, DNM2, MED28, SHBG, KHDRBS1, WAS, TUBB, WIPF1, HSPA1A, CARS, ACTB, PTPN18, WASF2, WASF1, CD2AP, PTPN12, MEFV, ABL1, CD2, FASLG, BZW2, RPL36,
Protein Size: 416

Molecular Weight: 47 kDa

Gene ID: 9051

NCBI Accession: NM_003978, NP_003969

UniProt: O43586