DYRK2 antibody (C-Term)

Catalog No. ABIN2789798

This anti-DYRK2 antibody is a Rabbit Polyclonal antibody detecting DYRK2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for DYRK2 antibody (C-Term) (ABIN2789798)

Target: DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DYRK2 Antibody

Binding Specificity: C-Term

Sequence: LFLDFLKQCL EWDPAVRMTP GQALRHPWLR RRLPKPPTGE KTSVKRITES

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DYRK2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 528 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DYRK2

Target: DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))

Alternative Name: DYRK2

Background: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro.
Alias Symbols: FLJ21217, FLJ21365
Protein Interaction Partner: SP100, WDR62, ZBTB9, LZTS2, KXD1, IKZF1, NR1I2, RB1CC1, DYRK4, DYRK2, TTN, HSP90AA1, TERT, APP, UBC, SIAH2, SSBP2, KATNA1, VPRBP, DAP3, TUBA3C, RPS2, RPLP0, RPL18, RPL7A, RPL7, RPL4, RPA1, SLC25A3, PDHB, PCMT1, NPM1, MDM2, HSPA8, HSPA6, HSPA5, HSPA1B, HSP
Protein Size: 528

Molecular Weight: 60 kDa

Gene ID: 8445

NCBI Accession: NM_003583, NP_003574

UniProt: Q92630

Pathways: Regulation of Carbohydrate Metabolic Process