Peroxiredoxin 4 antibody (N-Term)

Catalog No. ABIN2789800

This Rabbit Polyclonal antibody specifically detects Peroxiredoxin 4 in WB. It exhibits reactivity toward Human, Rat, Horse, Cow, Guinea Pig, Rabbit and Dog.

Quick Overview for Peroxiredoxin 4 antibody (N-Term) (ABIN2789800)

Target: Peroxiredoxin 4 (PRDX4)

Reactivity: Human, Rat, Horse, Cow, Guinea Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Peroxiredoxin 4 Antibody

Binding Specificity: N-Term

Sequence: LLLFLLPAGA VQGWETEERP RTREEECHFY AGGQVYPGEA SRVSVADHSL

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRDX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PRDX4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxiredoxin 4

Target: Peroxiredoxin 4 (PRDX4)

Alternative Name: PRDX4

Background: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
Alias Symbols: AOE37-2, PRX-4
Protein Interaction Partner: HUWE1, UBC, NEDD8, MDM2, SUMO1, EED, BMI1, TUBG1, TLN1, TBXA2R, NPM1, CSNK1E, US3, GLTPD2, ALG12, env, RCHY1, PRDX3, CFHR3, UBL4A, VTN, PRDX2, SULT2A1, PLG, PRDX1, COX1, LBP, NR4A1, CFHR1, CYP27A1, CLIC1, APOB, A1BG, ZNF593, CUL2, CUL3, SIRT7, SUMO4, SUMO
Protein Size: 271

Molecular Weight: 29 kDa

Gene ID: 10549

NCBI Accession: NM_006406, NP_006397

UniProt: Q13162