Peroxiredoxin 4 antibody (Middle Region)

Catalog No. ABIN954101

The Rabbit Polyclonal anti-Peroxiredoxin 4 antibody is suitable to detect Peroxiredoxin 4 in samples from Human and Mouse. It has been validated for WB, IHC (p) and EIA.

Quick Overview for Peroxiredoxin 4 antibody (Middle Region) (ABIN954101)

Target: Peroxiredoxin 4 (PRDX4)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Peroxiredoxin 4 Antibody

Binding Specificity: AA 89-118, Middle Region

Specificity: This antibody reacts to PRDX4.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 89-118 amino acids from the Central region of human PRDX4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Peroxiredoxin 4

Target: Peroxiredoxin 4 (PRDX4)

Alternative Name: Peroxiredoxin-4 / PRDX4

Background: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.Synonyms: AOE37-2, Antioxidant enzyme AOE372, PRDX-4, Prx-4, Prx-IV, Prx4, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372

Molecular Weight: 30540 Da

Gene ID: 10549

NCBI Accession: NP_006397