CDC14A antibody (C-Term)

Catalog No. ABIN2789804

The Rabbit Polyclonal anti-CDC14A antibody has been validated for WB. It is suitable to detect CDC14A in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for CDC14A antibody (C-Term) (ABIN2789804)

Target: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC14A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDC14A Antibody

Binding Specificity: C-Term

Sequence: DDDVEMKNGI TQGDKLRALK SQRQPRTSPS CAFRSDDTKG HPRAVSQPFR

Predicted Reactivity: Cow: 100%, Dog: 87%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CDC14A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 594 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC14A

Target: CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

Alternative Name: CDC14A

Background: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
Alias Symbols: cdc14, hCDC14
Protein Interaction Partner: CHRM1, CDC6, CDC25B, POLR2A, NPM1, FZR1, TP53, CCNB1, KIF20A, BRAP,
Protein Size: 594

Molecular Weight: 66 kDa

Gene ID: 8556

NCBI Accession: NM_003672, NP_003663

UniProt: Q9UNH5