NCF2 antibody (C-Term)

Catalog No. ABIN2789807

This anti-NCF2 antibody is a Rabbit Polyclonal antibody detecting NCF2 in WB. Suitable for Human, Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for NCF2 antibody (C-Term) (ABIN2789807)

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Reactivity: Human, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCF2 Antibody

Binding Specificity: C-Term

Sequence: TVGDQGFPDE PKESEKADAN NQTTEPQLKK GSQVEALFSY EATQPEDLEF

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rabbit: 75%

Characteristics: This is a rabbit polyclonal antibody against NCF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NCF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 526 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCF2

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Alternative Name: NCF2

Background: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.
Alias Symbols: FLJ93058, NCF-2, NOXA2, P67-PHOX, P67PHOX
Protein Interaction Partner: RAC1, GOLGA2, KIFAP3, S100A9, S100A8, NCF1, NCF4, GNB1, GNAI3, GNAI2, GNAI1, UBD, TRAF4, SYTL1, PRDX6, RAC2, CYBB, CYBA, CDC42, PRKDC, ACTB,
Protein Size: 526

Molecular Weight: 60 kDa

Gene ID: 4688

NCBI Accession: NM_000433, NP_000424

UniProt: P19878