S1PR1 antibody (C-Term)

Catalog No. ABIN2789809

This anti-S1PR1 antibody is a Rabbit Polyclonal antibody detecting S1PR1 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse and Guinea Pig.

Quick Overview for S1PR1 antibody (C-Term) (ABIN2789809)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-S1PR1 Antibody

Binding Specificity: C-Term

Sequence: SLVRTRSRRL TFRKNISKAS RSSEKSLALL KTVIIVLSVF IACWAPLFIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against S1PR1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 382 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: S1PR1

Background: The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.
Alias Symbols: CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1
Protein Interaction Partner: UBC, CMSS1, WWP2, TRIP6, CAV1, HTR1D, PDGFRB, AKT1, GNAI3, GNAI1, HTR1A,
Protein Size: 382

Molecular Weight: 43 kDa

Gene ID: 1901

NCBI Accession: NM_001400, NP_001391

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2