DNAJA3 antibody (C-Term)

Catalog No. ABIN2789841

Product Details anti-DNAJA3 Antibody

Target: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ETDVEGTVNG VTLTSSGGST MDSSAGSKAR REAGEDEEGF LSKLKKMFTS

Predicted Reactivity: Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DNAJA3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 480 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNAJA3

Target: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Alternative Name: DNAJA3 (DNAJA3 Products)

Background: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein.
Alias Symbols: FLJ45758, TID1, hTid-1
Protein Interaction Partner: HUWE1, STK16, TCF19, FOSL2, PCSK9, ALS2CR11, FRMD6, FAM214B, MYO15B, GCC1, NOC4L, OSGIN1, INPP5J, IRS4, UBC, KDM1A, CARM1, PRMT6, LATS2, EGFR, HSP90AA1, HSPA1A, HDAC11, NOS2, SMAD9, RPS18, MYO1C, CLTC, NDUFS7, UQCRQ, SCFD1, CRK, HSPA9, GFI1B, COIL, USP7,
Protein Size: 480

Molecular Weight: 52 kDa

Gene ID: 9093

NCBI Accession: NM_005147, NP_005138

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity