TLL1 antibody (C-Term)

Catalog No. ABIN2789905

This anti-TLL1 antibody is a Rabbit Polyclonal antibody detecting TLL1 in WB. Suitable for Human, Horse, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Cow and Rabbit.

Quick Overview for TLL1 antibody (C-Term) (ABIN2789905)

Target: TLL1 (Tolloid-Like 1 (TLL1))

Reactivity: Human, Horse, Mouse, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLL1 Antibody

Binding Specificity: C-Term

Sequence: DASVQRKGFQ ATHSTECGGR LKAESKPRDL YSHAQFGDNN YPGQVDCEWL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TLL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TLL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1013 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLL1

Target: TLL1 (Tolloid-Like 1 (TLL1))

Alternative Name: TLL1

Background: This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ASD6, TLL
Protein Interaction Partner: UBC, APP, CHRD,
Protein Size: 1013

Molecular Weight: 115 kDa

Gene ID: 7092

NCBI Accession: NM_012464, NP_036596

UniProt: O43897