CABLES1 antibody (C-Term)

Catalog No. ABIN2789954

This Rabbit Polyclonal antibody specifically detects CABLES1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for CABLES1 antibody (C-Term) (ABIN2789954)

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABLES1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CABLES1 Antibody

Binding Specificity: C-Term

Sequence: IRSLKREMRK LAQEDCGLEE PTVAMAFVYF EKLALKGKLN KQNRKLCAGA

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CABLES1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CABLES1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 633 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CABLES1

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Alternative Name: CABLES1

Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers.Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CABLES, FLJ35924, HsT2563, IK3-1, CABL1
Protein Interaction Partner: CDK5, ALB, TDRD7, CCNA1, TP73, TP53, ABL1, CCNE1, CDK3,
Protein Size: 633

Molecular Weight: 67 kDa

Gene ID: 91768

NCBI Accession: NM_001100619, NP_001094089

UniProt: Q8TDN4