PACS1 antibody (C-Term)

Catalog No. ABIN2789968

The Rabbit Polyclonal anti-PACS1 antibody has been validated for WB. It is suitable to detect PACS1 in samples from Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PACS1 antibody (C-Term) (ABIN2789968)

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PACS1 Antibody

Binding Specificity: C-Term

Sequence: FLSKKPREKE VDSKSQVIEG ISRLICSAKQ QQTMLRVSID GVEWSDIKFF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PACS1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 366 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Alternative Name: PACS1

Background: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Alias Symbols: -
Protein Interaction Partner: UBC, GGA3, CSNK2A1, FGFR1OP, PPP2CA, VAMP4, CLCN7, PPP2CB, PKD2, JUN, IGF2R, FURIN, TRPV4, nef,
Protein Size: 366

Molecular Weight: 42 kDa

Gene ID: 55690

NCBI Accession: NM_018026

UniProt: Q6VY07